The sphere of nanomaterials has progressed dramatically over the previous a long time with vital contributions to the biomedical space. The physicochemical properties of nanomaterials, akin to the dimensions and construction, might be managed by means of manipulation of mass and warmth switch situations throughout synthesis. Particularly, microfluidic techniques with fast mixing and exact fluid management are preferrred platforms for creating acceptable synthesis situations. One notable instance of microfluidics-based synthesis is the event of lipid nanoparticle (LNP)-based mRNA vaccines with accelerated scientific translation and strong efficacy throughout the COVID-19 pandemic. Along with LNPs, microfluidic techniques have been adopted for the managed synthesis of a broad vary of nanomaterials. On this evaluate, we introduce the elemental rules of microfluidic applied sciences together with circulation field- and a number of field-based strategies for fabricating nanoparticles, and talk about their functions within the biomedical area. We conclude this evaluate by outlining a number of main challenges and future instructions within the implementation of microfluidic synthesis of nanomaterials.
