With the present developmental developments in nanotechnology, nanofibrous scaffolds are being extensively used. The therapeutic of fibrocartilaginous enthesis is a sluggish and complicated course of, and whereas current therapies have a sure impact on selling their therapeutic, these are related to some limitations. The nanofibrous scaffold has some great benefits of simple preparation, large supply of uncooked supplies, simple adjustment, simple modification, can mimic the pure construction and morphology of the fibrocartilaginous enthesis, and has good biocompatibility, which may compensate for current therapies and be mixed with them to advertise the restore of fibrocartilaginous enthesis. The nanofibrous scaffold can promote the therapeutic of fibrocartilaginous enthesis by controlling the morphology and guaranteeing managed drug launch. Therefore, the usage of nanofibrous scaffold with stimulative response options within the musculoskeletal system has led us to think about its potential software in fibrocartilaginous enthesis. Due to this fact, the therapeutic of fibrocartilaginous enthesis primarily based on a nanofibrous scaffold could also be a novel therapeutic method.